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Pharmacological gene therapy
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From Wikipedia, the free encyclopedia
Pharmacological gene therapy is a new field
that combines pharmacological therapy and gene therapy. It is used
either to prevent a defective gene from producing its protein or to
increase the concentration of normal protein produced in the body by
insertion of DNA or RNA fragments. It can also be using to generate
immunity from contagious disease, such as TB, via the process of DNA
vaccination.
Gene Therapeutics can be used to treat such conditions as Cystic
Fibrosis (via the addition of a normal CFTR gene), Haemophilia A or
even some of the complications of AIDS.
It uses a number of methods including: Gene augmentation Targeted
Inhibition (using Antisense or antigene technology) Cell Killing
(either direct or assisted) and DNA vaccination .
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